In this message delivered ahead of the Fourth UN High-Level Meeting on NCDs and Mental Health, and on the sidelines of the UN High-Level Interactive Dialogue on Determinants of Health, Spain’s Minister of Health, Hon. Dr. Mónica García Gómez, reminds us that tackling the root causes of poor health—social, environmental, and commercial—is essential for protecting future generations and building resilient, equitable health systems. Spain calls for bold political action to put equity and prevention at the heart of global health policy.